2Shred: The Ultimate Non-Stimulant Thermogenic

Burn Fat Around the Clock

When it comes to fat loss, just like muscle building, efficiency and effectiveness is of the utmost importance. It is also well known that you can’t build quality muscle mass just by lifting weights, you also need adequate nutrition and precise supplementation.

Fat loss is the same, but it shouldn’t come at the cost of overstimulation, burnout, or disrupted sleep. That’s why we created 2Shred — an innovative and next-generation non-stimulant weight management system designed specifically to support 24/7 fat-burning, improved metabolic health, and appetite control, all without a single milligram of caffeine.

Powered by clinically studied ingredients that work synergistically to ignite thermogenesis, enhance lipolysis, support lean muscle, and curb cravings, 2Shred helps you stay in fat-burning mode — day and night.

Let’s look at how 2Shred works and how you can effectively incorporate this system into your plan.

 

2Shred Ingredient Breakdown

2SHRED AM Blend

MitoBurn® (L-β-Aminoisobutyric Acid) - 500mg

MitoBurn® (L-BAIBA) has a unique mechanism that mimics the body’s natural fat-burning signal and activating brown adipose tissue (BAT) to generate heat and burn stored fat. It can boost fat oxidation while helping to maintain lean muscle — making it ideal during calorie deficits.

Research shows that 500mg of L-BAIBA has incredible effects on metabolism:

  • White-to-Brown Fat Conversion: L-BAIBA can trigger “browning” of white adipose tissue. This process helps to convert energy-storing white fat into energy-burning, mitochondria rich brown-like fat cells, which are much more metabolically efficient.
  • Enhanced Fat Oxidation: Studies demonstrate that L-BAIBA increases fatty acid oxidation in both the liver and muscle tissue, helping your body more efficiently use fat as a fuel source.
  • Improved Glucose Metabolism: L-BAIBA has also been shown to improve insulin sensitivity and glucose tolerance. This can help to create a more favorable metabolic environment for fat loss.
  • Anti-Inflammatory: Research indicates L-BAIBA can reduce inflammation markers associated with obesity and metabolic dysfunction, helping create a healthier internal environment.

Sinetrol® Xpur (Citrus Extract Blend) - 450mg

A specific blend of citrus polyphenols, Sinetrol® has been clinically shown to reduce abdominal fat, stimulates lipolysis (the breakdown of fat cells), and delivers powerful antioxidant support to optimize your metabolic health. These polyphenols work synergistically through pathways that include phosphodiesterase inhibition, enhancement of lipolysis, and modulation of metabolic signaling, which includes the “browning” of white adipose tissue.

A 12-week clinical study shows that individuals who were supplementing Sinetrol® as a part of their regimen had seen significant improvements in several health markers.

  • Body weight decreased by 3.28%
  • Abdominal fat decreased by 9.73%
  • Waist circumference decreased by 5.71%
  • Hip circumference decreased by 4.71%
  • C-reactive protein decreased by 22.87%
  • Fasting blood glucose decreased by 9.95%
  • Free fatty acid levels increased, showing enhanced lipolytic activity

Coleus forskohlii (20% Forskolin Standardized) - 250mg

This classic thermogenic Ayurvedic herb works by increasing cyclic AMP (cAMP) levels, which help to ramp up fat breakdown and calorie burn. Forskolin has also been shown to help preserve muscle mass and elevate energy — all without overstimulating the nervous system.

Clinical research has shown promise with these outcomes. A 12-week study on overweight and obese men showed that supplementation with forskolin significantly decreased body fat percentage and fat mass while showing retainment of lean body tissue.

This data makes forskolin a powerful tool in the goal of body fat reduction, while also preserving hard earned muscle.

DNF-10® (Hydrolyzed Yeast Extract) - 250mg

Targeting hunger at its source, DNF-10® shows effective ability to regulate appetite hormones like ghrelin and leptin, which contribute to significant reductions in caloric intake over time. It also has been shown to inhibit specific enzymes that are directly involved with fatty acid synthesis.

DNF-10® has strong clinical backing for reducing body weight and waist circumference, all while keeping cravings and overall caloric intake in check.

InnoSlim® (Astragalus membranaceous & Panax notoginseng) - 125mg

InnoSlim® has been shown to enhance glucose uptake into muscle while also reducing fat storage, thanks in part to AMPK activation, which acts as a metabolic master switch. It also has been shown to support healthy blood sugar levels, making it essential for long-term fat-loss sustainability.

aXivite® (Phenylcapsaicin) - 100mg (yielding 1mg)

The next generation of capsaicin, aXivite®, an innovative form of phenylcapsaicin, can boost thermogenesis and metabolic rate without the intense burning sensation of traditional chili-based extracts. Its sustained-release design delivers a steady fat-burning effect over time while also offering significantly higher bioavailability than traditional capsaicin. How much more bioavailable? Approximately 8x more, meaning you can reap all the benefits with a much smaller dose.

aXivite® has a duel pronged approach as well. On the one hand it can enhance fat breakdown during exercise, which can help your body use fat as an efficient fuel source and promote greater fat burning throughout the day. On the other hand, it can also improve exercise performance by reducing feelings of perceived exertion, which can help you train harder and longer.

Unmatched wanted to give you want all the benefits of capsaicin with none of the traditional burn, making the inclusion of aXivite® in 2Shred AM a no brainer.

GBB (Gamma-Butyrobetaine) - 50mg

Known as the “pre-carnitine” molecule, GBB is known to raise the body’s natural production of L-carnitine, which in turn helps to shuttle fatty acids into the mitochondria to boost fat oxidation and convert them to energy. GBB is also known to create a clean, sweat-inducing burn without the crash. GBB’s dual action by both enhancing thermoregulation and carnitine production make it a crucial component to this AM formula.

Fucoxanthin (Seaweed Extract) - 25mg

Derived from seaweed, Fucoxanthin targets visceral fat, the hard-to-burn fat around your organs, by activating UCP1, a protein involved in thermogenic fat metabolism. Fucoxanthin can also effectively support metabolic rate and inflammation control. Paired alongside ingredients like MitoBurn® and Sinetrol® who’s mechanisms include converting white fat cells into more metabolically efficient fat cells, fucoxanthin adds especially targeted benefits in the goal of overall fat loss.

 

2SHRED PM Blend

The PM blend of this system will incorporate most of the ingredients above but will also touch on a few key factors that need to be enhanced in the evening hours prior to sleep; Relaxation, cortisol management, as well as craving control.

Sinetrol® Xpur - 450mg (full clinical dose)

Coleus forskohlii - 250mg (full clinical dose)

DNF-10 - 250mg (full clinical dose)

InnoSlim® - 125mg (full clinical dose)

KSM-66® Ashwagandha – 600mg

KSM-66® is a full-spectrum ashwagandha root extract that is one of the most well researched adaptogenic ingredients known in the industry today. This potent adaptogen has been shown to effectively modulate the body’s stress response and lower cortisol levels, helping combat stress-related eating and fat gain, while also preserving muscle mass during dieting phases. While KSM-66® does have some performance related benefits for strength and endurance, including this adaptogen in the PM blend of 2Shred can help to optimize recovery, reduce stress related eating, and help to promote an environment that will be beneficial for fat loss while you are at rest.

L-Theanine – 200mg

L-Theanine, an amino acid often found in green tea, can help promote a calm, focused, and consistent feeling without any sedation. By also reducing stress and emotional eating, theanine plays a critical role in weight management adherence — especially during high-stress dieting phases.

L-Theanine works by increasing alpha brain wave activity, which creates the calm and focused feeling described above. Its stress and anxiety reducing benefits come from boosting GABA production. This relaxing feeling can help to mitigate nighttime snacking and overconsumption while also helping aid in a faster time to sleep, which is key for fat loss.

SaffSerene® (Saffron Extract) – 15mg

Clinical research has shown that this unique ingredient can regulate appetite, curb emotional eating, and elevate mood. Saffron’s benefits stem from modulating neurotransmitter activity, particularly serotonin levels. By supporting healthy levels of these hormones, saffron can help you stay mentally dialed in and motivated throughout your fat-loss journey.

Although appetite control is a main benefit of saffron, it also has impressive antioxidant properties and may be effective at improving mood and sleep quality. Including saffron in this PM blend is the perfect ending ingredient to round out this formula for your nighttime fat burning goal.

 

The Bottom Line: Shred Without the Stim

With a market that is dominated by high-stimulant formulas, a non-stimulant, round-the-clock weight management system can offer a smarter, more sustainable path to body recomposition.

By supporting metabolism, appetite control, thermogenesis, and energy production—without the crash or overstimulation, this Unmatched® 2Shred formula can be seamlessly integrated into any routine, no matter when you train.

Whether you’re caffeine-sensitive, stacking with other products, or simply seeking consistent, long-term results, a well-formulated non-stimulant thermogenic can give your body the support it needs to burn fat, control appetite, and support healthy cortisol levels efficiently without compromise. It's not just about intensity, it's about strategy, consistency, and science-backed results.

This is next-level thermogenesis. This is how you can become … Unmatched.

 

References

  • Roberts, LeeD., et al. “β-Aminoisobutyric Acid Induces Browning of White Fat and Hepatic β-Oxidation and Is Inversely Correlated with Cardiometabolic Risk Factors.” Cell Metabolism, vol. 19, no. 1, Jan. 2014, pp. 96–108, doi:10.1016/j.cmet.2013.12.003. https://pmc.ncbi.nlm.nih.gov/articles/PMC4017355/
  • Jung, Tae Woo, et al. “BAIBA Attenuates Insulin Resistance and Inflammation Induced by Palmitate or a High Fat Diet via an AMPK–PPARδ-Dependent Pathway in Mice.” Diabetologia, vol. 58, no. 9, 24 June 2015, pp. 2096–2105, doi:10.1007/s00125-015-3663-z. https://pubmed.ncbi.nlm.nih.gov/26105792/
  • Dallas, Constantin, et al. “Clinical Study to Assess the Efficacy and Safety of a Citrus Polyphenolic Extract of Red Orange, Grapefruit, and Orange (Sinetrol-XPur) on Weight Management and Metabolic Parameters in Healthy Overweight Individuals.” Phytotherapy Research, vol. 28, no. 2, 3 Apr. 2013, pp. 212–218, doi:10.1002/ptr.4981. https://pubmed.ncbi.nlm.nih.gov/23554029/
  • Romain, Cindy, et al. “Sixteen Weeks of Supplementation with a Nutritional Quantity of a Diversity of Polyphenols from Foodstuff Extracts Improves the Health-Related Quality of Life of Overweight and Obese Volunteers: A Randomized, Double-Blind, Parallel Clinical Trial.” Nutrients, vol. 13, no. 2, 2 Feb. 2021, pp. 492–492, doi:10.3390/nu13020492. https://pmc.ncbi.nlm.nih.gov/articles/PMC7913070/
  • Chen, J. Y., Peng, S. Y., Cheng, Y. H., Lee, I. T., & Yu, Y. H. (2021). Effect of Forskolin on Body Weight, Glucose Metabolism and Adipocyte Size of Diet-Induced Obesity in Mice. Animals : an open access journal from MDPI, 11(3), 645. https://doi.org/10.3390/ani11030645
  • Henderson, S., Magu, B., Rasmussen, C., Lancaster, S., Kerksick, C., Smith, P., Melton, C., Cowan, P., Greenwood, M., Earnest, C., Almada, A., Milnor, P., Magrans, T., Bowden, R., Ounpraseuth, S., Thomas, A., & Kreider, R. B. (2005). Effects of coleus forskohlii supplementation on body composition and hematological profiles in mildly overweight women. Journal of the International Society of Sports Nutrition, 2(2), 54–62. https://doi.org/10.1186/1550-2783-2-2-54
  • Seika Kamohara, Yoshiko Terasaki, Itsuko Horikoshi, Satoshi Sunayama, Safety of a Coleus forskohlii formulation in healthy volunteers, Personalized Medicine Universe, Volume 4, 2015, Pages 63-65, ISSN 2186-4950, https://doi.org/10.1016/j.pmu.2015.01.001
  • Godard, Michael P., et al. “Body Composition and Hormonal Adaptations Associated with Forskolin Consumption in Overweight and Obese Men.” Obesity Research, vol. 13, no. 8, Aug. 2005, pp. 1335–1343, doi:10.1038/oby.2005.162. https://onlinelibrary.wiley.com/doi/10.1038/oby.2005.162
  • Loftus, Hayley, et al. “Coleus Forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial.” Nutrients, vol. 7, no. 11, 17 Nov. 2015, pp. 9508–9522, doi:10.3390/nu7115483. https://pmc.ncbi.nlm.nih.gov/articles/PMC4663611/
  • Jung, Eun Young, et al. “Yeast Hydrolysate Can Reduce Body Weight and Abdominal Fat Accumulation in Obese Adults.” Nutrition, vol. 30, no. 1, Jan. 2014, pp. 25–32, doi:10.1016/j.nut.2013.02.009. https://pubmed.ncbi.nlm.nih.gov/24290594/
  • Jung, Eun Young, et al. “Effects of Yeast Hydrolysate on Hepatic Lipid Metabolism in High-Fat-Diet-Induced Obese Mice: Yeast Hydrolysate Suppresses Body Fat Accumulation by Attenuating Fatty Acid Synthesis.” Annals of Nutrition and Metabolism, vol. 61, no. 2, 2012, pp. 89–94, doi:10.1159/000338441. https://pubmed.ncbi.nlm.nih.gov/22889874/
  • Eun Young Jung, et al. “Low Dose Yeast Hydrolysate in Treatment of Obesity and Weight Loss.” Preventive Nutrition and Food Science, vol. 22, no. 1, 31 Mar. 2017, pp. 45–49, doi:10.3746/pnf.2017.22.1.45. https://pmc.ncbi.nlm.nih.gov/articles/PMC5383141/
  • Jiménez-Martínez, Pablo, et al. “Effects of Different Phenylcapsaicin Doses on Resistance Training Performance, Muscle Damage, Protein Breakdown, Metabolic Response, Ratings of Perceived Exertion, and Recovery: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial.” Journal of the International Society of Sports Nutrition, vol. 20, no. 1, 22 Apr. 2023, doi:10.1080/15502783.2023.2204083. https://pmc.ncbi.nlm.nih.gov/articles/PMC10124973/
  • Jiménez-Martínez, Pablo, et al. “Effects of Phenylcapsaicin on Aerobic Capacity and Physiological Parameters in Active Young Males: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial.” Frontiers in Physiology, vol. 14, 9 May 2023, doi:10.3389/fphys.2023.1190345. https://pmc.ncbi.nlm.nih.gov/articles/PMC10203624/
  • Conrado de Freitas, Marcelo, et al. “Acute Capsaicin Supplementation Improves Resistance Training Performance in Trained Men.” Journal of Strength and Conditioning Research, July 2017, p. 1, doi:10.1519/jsc.0000000000002109. https://pubmed.ncbi.nlm.nih.gov/28682933/
  • Turck, Dominique, et al. “Safety of Phenylcapsaicin as a Novel Food pursuant to Regulation (EU) 2015/2283.” EFSA Journal, vol. 17, no. 6, June 2019, doi:10.2903/j.efsa.2019.5718. https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2019.5718
  • Chandrasekhar, K, et al. “A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults.” Indian Journal of Psychological Medicine, vol. 34, no. 3, 2012, pp. 255–62, doi:10.4103/0253-7176.106022. https://pmc.ncbi.nlm.nih.gov/articles/PMC3573577/
  • Ziegenfuss, Tim, et al. “Effects of an Aqueous Extract of Withania Somnifera on Strength Training Adaptations and Recovery: The STAR Trial.” Nutrients, vol. 10, no. 11, 20 Nov. 2018, p. 1807, doi:10.3390/nu10111807. https://pmc.ncbi.nlm.nih.gov/articles/PMC6266766/
  • Mashmoul, Maryam, et al. “Saffron: A Natural Potent Antioxidant as a Promising Anti-Obesity Drug.” Antioxidants, vol. 2, no. 4, 1 Dec. 2013, pp. 293–308, doi:10.3390/antiox2040293. https://pmc.ncbi.nlm.nih.gov/articles/PMC4665515/
  • Seyedeh Farzaneh Omidkhoda, and Hossein Hosseinzadeh. “Saffron and Its Active Ingredients against Human Disorders: A Literature Review on Existing Clinical Evidence.” PubMed, vol. 25, no. 8, 1 Aug. 2022, pp. 913–933, doi:10.22038/ijbms.2022.63378.13985. https://pmc.ncbi.nlm.nih.gov/articles/PMC9464341/
  • Lopresti, Adrian L, et al. “Effects of Saffron on Sleep Quality in Healthy Adults with Self-Reported Poor Sleep: A Randomized, Double-Blind, Placebo-Controlled Trial.” Journal of Clinical Sleep Medicine, vol. 16, no. 6, 14 Feb. 2020, doi:10.5664/jcsm.8376. https://pmc.ncbi.nlm.nih.gov/articles/PMC7849671/
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