Longevity Sleep

Introducing Longevity Sleep — a next-generation night-time formulation specifically engineered to do more than just help you fall asleep. This innovative blend is built around clinically validated ingredients like ZMA, GABA, Glycine, PeptiSleep™, Senactiv®, and Melatonin, among others, that work synergistically together to optimize your body’s recovery, calm the mind, and promote deep, restorative, quality sleep patterns while increasing your health-span.

Longevity Sleep goes beyond traditional sleep aids by addressing not just sleep quantity, but more importantly sleep quality, cellular, brain and muscle repair, and long-term vitality. 

From enhancing GABAergic relaxation and supporting neurotransmitter balance, to stimulating cellular renewal and muscle regeneration during deep sleep, every serving is carefully designed to help you wake up sharper, stronger, leaner and fully recovered so you can tackle your days, career, cardio and workouts. Whether you're chasing performance, longevity, or stress resilience, Longevity Sleep can deliver the nightly reset your body deserves.

ZMA (Vitamin B6, Magnesium, Zinc)

ZMA is a synergistic combination of zinc, magnesium, and vitamin B6 that has become a staple, particularly among athletes, bodybuilders, and individuals with demanding training schedules. While originally marketed for its potential testosterone-boosting benefits, ZMA is now widely appreciated and accepted for its ability to support deep, restorative sleep, which is essential for muscle recovery, hormone regulation, and mental clarity.

One of the core components of ZMA is magnesium, which a mineral known for its role in calming the nervous system and promoting relaxation. Magnesium helps regulate GABA - a key neurotransmitter involved in reducing brain activity and easing the body into a restful state. Deficiencies in magnesium are extremely common, especially in active individuals, and are strongly linked to poor sleep quality, frequent nighttime awakenings, and increased stress. Supplementing with magnesium as part of ZMA can help promote deeper sleep cycles and improve overall sleep efficiency.

Zinc, on the other hand, plays a complementary role in supporting immune function, cellular repair, and hormonal balance, all of which are vital processes during restorative sleep. Emerging research also suggests zinc may contribute to enhanced REM sleep and improved mood regulation. Meanwhile, vitamin B6 supports the production of neurotransmitters like serotonin and melatonin, both of which are crucial for regulating the sleep-wake cycle.

When taken about 30–60 minutes before bed, ZMA can help promote more restful, uninterrupted sleep and better next-day recovery without causing grogginess. It's a non-habit-forming, nutrient-based mixture that supports not only sleep, but also recovery, immune health, testosterone, and overall performance, making it a well-rounded addition to any night-time health-span routine.

L-Glycine

L-Glycine is an amino acid that possesses physiological effects independent of its function as a ‘building block’ to protein. In glycine’s case, its physiological effects stem from its role as a neurotransmitter in the human brain.

Three methodologically-sound studies have investigated glycine’s effect on sleep and sleep quality in humans – and each used the same serving size as that found in Unmated LONGEVITY SLEEP - 3 grams. In studies conducted in 2006 and 2007, ingestion of 3 grams of glycine prior to sleep was found to have both subjective and objective positive effects on sleep. Subjectively, participants reported more satisfactory sleep, less daytime sleepiness, and improved cognitive function. Objectively, PSG measurements revealed less latency to sleep onset and deep sleep. These results were confirmed in another 2012 study which focused principally on glycine-dependent improvements to daytime cognitive function in sleep-deprived volunteers.

Overall, these human trials suggest a possible role for glycine in the regulation of beneficial sleep cycles at a serving size of 3 grams.

Gamma-aminobutyric acid (GABA)

GABA (Gamma-Aminobutyric Acid) is the body’s primary inhibitory neurotransmitter responsible for calming brain activity, reducing neuronal excitability, and promoting a sense of relaxation. Supplementing with GABA, particularly at higher doses of around 3 grams, has been shown to produce noticeable effects on sleep quality, sleep latency (the time it takes to fall asleep), and overall mental calmness before bedtime.

At this dose, GABA has the potential to cross the blood-brain barrier more effectively, leading to greater activation of GABA-A receptors. This then helps slow down overactive neural firing that can cause restlessness, anxiety, or racing thoughts, factors that commonly interfere with falling individuals falling asleep. Users often report a calming, mild sedative-like effect within 30 to 60 minutes of ingestion, making GABA particularly useful for those with difficulty winding down at night or dealing with stress-induced insomnia.

Studies have shown that GABA supplementation can increase alpha brain wave activity, a brainwave state associated with relaxed alertness and transition into sleep. Additionally, GABA may increase the time spent in deep (slow wave) sleep, which is crucial for physical restoration, hormone production, and memory consolidation. Unlike melatonin, which primarily affects the timing of sleep, GABA directly promotes deeper and more stable sleep architecture.

GABA is also naturally produced by the body, so supplementing with it is generally well-tolerated, especially when taken at night. A 3g dose, like what is found in LONGEVITY SLEEP, may be ideal for those seeking a natural, non-habit-forming alternative to prescription sleep medications, especially when combined with other synergistic calming nutrients like tryptophan, magnesium, or glycine. 

L-Tryptophan

L-Tryptophan is an essential amino acid, and one of the most critical in the human body. Tryptophan acts as a key biological precursor to both serotonin (one of the body’s principal neurotransmitters regulating mood, appetite, and sleep) and niacin (a vitamin and a crucial biological intermediate).

Among dietary supplements or ingredients purported to regulate the sleep-wake cycle, tryptophan is perhaps one of the most well-studied. With studies as far back as 40 years, the body of literature pertaining to tryptophan’s sedative effects is vast and varied. Despite this and therefore potential for disagreement or conflicting data, scientific consensus exists that tryptophan does in fact exert positive effects on the regulation of the sleep wake cycle in humans, which has been seen in a handful of placebo-controlled trials in humans.

One placebo-controlled, double-blind trial involved healthy volunteers ingesting either 1.2 grams or 2.4 grams of tryptophan prior to sleep. Blood and urine measurements were taken at regular intervals, and sleep was measured both objectively (latency to sleep) and subjectively using the Stanford Sleepiness scale. Both serving sizes of tryptophan were highly correlated with a significant reduction in sleep latency and significant improvements to subjective sleep quality on the Stanford Sleepiness Scale.

Results such as this have been reproduced in dozens of clinical trials involving healthy/normal and sleep-disturbed subjects, men and women, younger and older participants, and featuring serving sizes as low as 500mg and high as 15 grams. These studies nearly universally reflect that exogenous tryptophan supplementation is positively correlated with an improvement in sleep quality and an objective reduction in sleep latency – with the best effect’s resultant from a 1 gram to 1.5 gram serving size, which we have opted for in our Longevity Sleep formula.

Tart Cherry Concentrate (Prunus cerasus) (Fruit)

Tart cherry concentrate has gained attention in recent years as a popular natural aid for improving sleep quality and duration. One of its primary benefits lies in its ability to support the body's natural melatonin production. Tart cherries, especially Montmorency tart cherries, are one of the few natural sources of melatonin, a hormone that notably regulates the sleep-wake cycle. By increasing circulating melatonin levels, tart cherry concentrate may help reduce the time it takes to fall asleep and support deeper, more restful sleep.

But melatonin isn’t where tart cherries stop. Tart cherry concentrate is also rich in polyphenols and anthocyanins, two compounds with strong inflammatory mediating and antioxidant properties. Chronic inflammation and oxidative stress can commonly disrupt sleep quality and recovery, especially in individuals under physical or psychological stress. By reducing key inflammatory markers and oxidative load, tart cherry may support the body’s natural recovery processes during sleep, leading to improved restfulness and reduced nighttime awakenings.

In randomized controlled trials, participants who consumed tart cherry juice or concentrate experienced significant increases in total sleep time and sleep efficiency compared to placebo. These effects are particularly valuable for athletes, shift workers, and individuals with mild insomnia or sleep disturbances. Additionally, the benefits are achieved without dependency or grogginess, making tart cherry concentrate a gentle, natural alternative to synthetic sleep aids.

PeptiSleep™ (Rice (Oryza sativa) protein hydrolysate)

PeptiSleep™, a trademarked rice (Oryza sativa) protein hydrolysate, is an innovative, natural peptide-based solution for improving sleep quality, latency, and overall nighttime recovery. Leveraging the calming and neuroactive properties of bioactive rice-derived peptides to support the body’s natural sleep mechanisms, these peptides are produced through a controlled enzymatic hydrolysis process, yielding small, functional peptides that interact with neurotransmitter systems involved in stress reduction and relaxation.

One of the key mechanisms behind PeptiSleep™’s efficacy is its ability to effectively reduce cortisol levels, which are often the culprit when it comes to stress and poor sleep. By modulating GABAergic pathways and supporting GABA function, PeptiSleep™ addresses both stress and wakefulness signaling, allowing for a smooth, anxiety-free transition into sleep helping users stay asleep longer without disruption. 

Preliminary research and emerging human trials on PeptiSleep™ suggest significant improvements in sleep efficiency, duration, and morning alertness, with one pilot study reporting:

• 61% of participants fell asleep faster
• 17% increase in deep sleep
• 13% increase in light sleep

These results show that sleep readiness, sleep scores, and key sleep metrics (like recovery) are improved with the implementation of PeptiSleep™ into a normal bedtime routine. 

PeptiSleep™ offers a gentle, natural, and effective approach to sleep support by leveraging rice-derived peptides to calm the mind and enhance sleep quality. Its non-sedating nature, plant-based origin, and synergy with other calming ingredients make it a standout choice for modern sleep wellness formulations.

Valerian Root Extract 4:1 (Valernia officinalis)

Valerian root is a commonly utilized herb all over the world. Coming from a flowering plant native to Europe and Asia primarily, it has been most used for its benefits towards insomnia and some anxiety disorders. The National sleep Foundation reports over 50% of American adults suffer from some sort of insomnia or sleep related difficulties. While the specific ingredient responsible for valerian roots activity has not yet fully been identified, it is believed that a combination of sesquiterpenoids and valepotriates (two compounds found within valerian) may be involved in its mechanism of action. This mechanism of action is exhibited through its binding potential to the subunit on the GABA-A receptors, which causes GABA to bind to the alpha subunit more effectively. We have talked about GABAs benefits on the human body in the context of sleep latency and quality in other sections, so valerian root still targets GABA receptors albeit through a different pathway. This binding essentially will make the neuron less responsive to stimulation by excitatory postsynaptic potentials, thus suppressing the central nervous system. Valerian has been shown to decrease the removal of GABA from the body, thus allowing GABA to stay around longer, equating to a higher quality and duration of sleep. Another proposed mechanism of action is that valernic acid inhibits an enzyme that destroys GABA, thus increasing its half-life and time within the body. 

Senactiv® (Panax notoginseng (Root) and Rosa roxburghii (Fruit) Extracts)

Senactiv®, derived from extracts of Panax notoginseng and Rosa roxburghii, has been shown to act in a few pathways to reenergize and rejuvenate cells within the body that take a beating daily. Ultimately this product falls within a category known as senolytics, or compounds that primarily work to induce cell death. This may not sound ideal as we need our cells to function, but the key is to ensure that these compounds are working on the right kinds of cells. The human body does contain many senescent cells, which are old cells and can deteriorate and then replicate. 

These senolytics work to promote health by speeding up the breakdown of these older cells as well as encouraging the growth of new, vibrant cells. The other benefit of Senactiv® and its ingredients is its ability to protect against muscle damage. Ginseng has been shown to help reduce the proinflammatory state that is associated with rigorous training. This can help reduce inflammation and jumpstart the recovery process of torn down muscle fibers so these cells can begin to scar and grow stronger. This is beneficial to sleep as this is the primary time when your body is recovering and building what has broken down repeatedly during training sessions or through the rigors of everyday life. 

Melatonin

Irregular sleep is a problem that is common amongst the population, and most are often searching for remedies to improve sleep quality and circadian rhythms. 

Melatonin is a neurohormone that is secreted by the pineal gland known for its sleep regulation properties. Its secretion is often suppressed by light, which when this occurs can often disrupt normal sleep patterns. When sleep patterns are disrupted and irregular, it can increase risks of certain health issues and premature aging. Supplementation exerts most of its benefits through decreased sleep latency and increased onset of sleep. This can also be related to its ability to work with biochemistry and decrease body temperature in users. 

Supplementation with melatonin is the most efficient way to increase melatonin levels prior to sleeping. However, diet and improvements in quality of life are also ways to improve normal melatonin secretion as well as normal circadian rhythm for better quality sleep. 

Melatonin secretion naturally declines as we get older so wearing blue light blocking glasses for some hours before bed, staying clear of anything such as screentime that may activate dopamine, and supplementing with melatonin can greatly help.

As our co-founder Kris Gethin always says, “your performance is dictated by your recovery, and sleep is when you recover, so supplement with Longevity Sleep” 

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